Confuse or stupefy (someone), especially with alcohol.
(archaic) Go on a drinking bout.
Late 16th century (in the sense ‘go on a drinking bout’): of unknown origin.
“You have no chance of any sense, he’s let the drink fuddle him.”
Originally: a bald head; a bald-headed person. In later use also: a pitiable, lowly, or foolish person; a shabby or unkempt person. Frequently used without article, as though a proper name.
Early 16th century; earliest use found in John Skelton (c1460–1529), poet. In some forms apparently partly from pilled + garlic and partly from peeled + garlic; in some forms apparently partly from pill + garlic and partly from peel + garlic.