Having failed to become what one might have been.
Late 18th century: French, past participle of manquer ‘to lack’.
“It’s sad, he wanted to be a writer and now he’s nothing but a reclusive manque.”
Something or someone that one vehemently dislikes/ A strong curse.
Early 16th century: from ecclesiastical Latin, ‘excommunicated person, excommunication’, from Greek anathema ‘thing dedicated’, (later) ‘thing devoted to evil, accursed thing’, from anatithenai ‘to set up’.