In low spirits from loss of hope or courage.
“She grew more despondent every day.”
“The situation was getting worse and it was hard not to be despondent.”
The last stage of life; old age.
Senectitude comes from the Medieval Latin noun senectitūdō meaning “old age,” which in turn comes from Classical Latin senectūs, a derivative of the noun senex meaning “old man.” Senectitude entered English in the late 1700s, more precisely, in 1796 in Jonathan Swift’s Gulliver’s Travels